home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
The Arsenal Files 6
/
The Arsenal Files 6 (Arsenal Computer).ISO
/
health
/
med9603.zip
/
M9630127.TXT
< prev
next >
Wrap
Text File
|
1996-02-27
|
2KB
|
33 lines
Document 0127
DOCN M9630127
TI Functional brain imaging in HIV-1-infected children born to seropositive
mothers.
DT 9603
AU Depas G; Chiron C; Tardieu M; Nuttin C; Blanche S; Raynaud C; Syrota A;
Service Hospitalier Frederic Joliot, CEA and INSERM U29, Orsay,; France.
SO J Nucl Med. 1995 Dec;36(12):2169-74. Unique Identifier : AIDSLINE
MED/96101642
AB The aim of this work was to study cerebral function in vertically
infected children with human immunodeficiency virus 1 (HIV-1). METHODS:
PET with 18F-labeled fluorodeoxyglucose (FDG) was performed in eight
children (2.5-5.5 yr): three with severe neurological symptoms and five
without. Quantitative analysis was based on gray matter cortical and
subcortical regions of interest for which glucose utilization was
measured. RESULTS: Diffuse hypometabolism and subcortical
hypermetabolism were found in the three children with severe
neurological signs; the five other children had temporo-occipital
cortical hypometabolism, mainly on the right side. CONCLUSION:
Functional cerebral abnormalities seem to precede clinical symptoms in
HIV-1infection of the brain in children.
DE Acquired Immunodeficiency Syndrome/TRANSMISSION AIDS Dementia
Complex/*RADIONUCLIDE IMAGING Brain/*RADIONUCLIDE IMAGING Case-Control
Studies Child, Preschool Deoxyglucose/*ANALOGS &
DERIVATIVES/DIAGNOSTIC USE Disease Transmission, Vertical Female
Fluorine Radioisotopes/*DIAGNOSTIC USE Human HIV Seropositivity
*HIV-1 Male Support, Non-U.S. Gov't *Tomography, Emission-Computed
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).